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Author Topic: Altus Pharmaceuticals Announces Presentation Of Phase 3 Trizytek Efficacy Data At The North American  (Read 2363 times)
February 21, 2010, 04:18:22 PM
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« Reply #15 on: February 21, 2010, 04:18:22 PM »

Persistent insomnia or daytime sleepiness is not a part of normal aging.
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The use of solid fuels for cooking and heating may cause high levels of indoor air pollution, which may then lead to the development of COPD.
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Regardless, research on the venom continued and eventually a long-acting peptide, teprotide, was isolated.
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It is thought to be caused by either genes or the environment (such as infections).
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Oral ingestion of the contents of a 15 mL DROP-TAINER® dispenser would be equivalent to 7.5 mg.
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The insulin should be clear and colorless.
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Nestle your baby in your arm in a cradle hold (see Multimedia File 4). This involves cradling the baby with your arm on the same side as the breast being presented.
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The higher the altitude at which a hyperbaric chamber is used, the greater the apparent descent can be simulated.
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Conditioned individuals have higher levels of oxygen consumption than deconditioned individuals ("couch potatoes") due to biological changes in the muscles from chronic exercise training.
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February 21, 2010, 08:37:02 PM
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« Reply #16 on: February 21, 2010, 08:37:02 PM »

In some cases, particularly when other conditions such as ovarian or adrenal gland tumors are suspected, CT and MRI scans may be ordered.
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Arteries are blood vessels that carry oxygenated blood away from the heart.
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Therefore, administration of MOTRIN Suspension is not recommended during labor and delivery.
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NSAIDs inhibit platelet aggregation and have been shown to prolong bleeding time in some patients.
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A teacher may think a student they cannot control has ADD, but in reality the true problem is simply a lack of discipline.
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GH is part of a cascade of hormones that, as the name implies, regulates the physical growth of the body.
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The common sites are found in the dependent portions of the pelvis: ovary, posterior cul-de-sac, broad ligament, uterosacral ligament, rectosigmoid colon, bladder, distal ureter.
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Cardiologists usually do cardiac catheterizations in a hospital.
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Disulfiram is used less frequently today because of side effects and high discontinuation rate among users.
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One such standardized procedure3,4 that has been recommended for use with disks to test the susceptibility of microorganisms to rifampin uses the 5 mcg rifampin disk.
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If the intestinal tract is damaged, the more "aggressive" treatment may be needed.
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February 22, 2010, 01:08:54 AM
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« Reply #17 on: February 22, 2010, 01:08:54 AM »

Sleeping pills and benzodiazepines (Valium and similar medicines) can build up faster in the blood when the liver doesn't work well.
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If cancer has spread, treatment may include biologic therapy or surgery to remove the primary tumor.
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If possible, beta-blockers should be withdrawn well before surgery takes place.
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One flexible–dose study had a starting dose of 30 mg once daily for 1 week before increasing it to 60 mg once daily.
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Grade 2 or 3 tears may have a defect that can be felt in the muscle, confirming the diagnosis.
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IN THIS ARTICLENon–Small-Cell Lung Cancer OverviewNon–Small-Cell Lung Cancer CausesNon–Small-Cell Lung Cancer SymptomsWhen to Seek Medical CareExams and TestsNon–Small-Cell Lung Cancer TreatmentMedical TreatmentMedicationsSurgeryOther TherapyNext StepsFollow-upPreventionOutlookSupport Groups and CounselingFor More InformationWeb LinksSynonyms and KeywordsAuthors and EditorsWhen to Seek Medical CareAny pain in the chest, side, or back; breathing problem; or cough that persists, worsens, or produces blood warrants an immediate visit to a health care provider.
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While a healthy body weight should also be a goal of treatment, it is important to remember that a reduction in weight (as little as 5%-10%) can have a dramatic benefit on lowering blood pressure and cholesterol levels and increasing insulin sensitivity.
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Medication to control the seizures and abnormal brain wave activity (anticonvulsants) usually has very little effect on language ability.
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The NIDDK is part of the National Institutes of Health of the U.S. Department of Health and Human Services.
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Kuru is another type of human prion brain infection.
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February 22, 2010, 05:50:58 AM
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« Reply #18 on: February 22, 2010, 05:50:58 AM »

This is especially important if you already have a problem with low blood pressure or take medicines to treat high blood pressure.
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The relative risk for myocardial infarction in current oral contraceptive users has been estimated to be 2 to 6. The risk is very low under the age of 30. However, there is the possibility of a risk of cardiovascular disease even in very young women who take oral contraceptives.
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Before undergoing any expensive diagnostic test, it is always wise to get a second medical opinion.
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The outlook for people with early-stage typical carcinoid lung tumors is usually very good.
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Owen Dahl, FACHE, CHBC, is a nationally recognized medical practice management consultant with over 26 years of experience in consulting for and managing medical practices and author of “Think Business! Medical Practice Quality, Efficiency, Profits” and “The Medical Practice Disaster Planning Workbook.
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In clinical trials related to the control of ventricular response in digitalized patients who had atrial fibrillation or atrial flutter, ventricular rate below 50/min at rest occurred in 15% of patients and asymptomatic hypotension occurred in 5% of patients.
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In some cases, the disorder may spontaneously disappear.
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When to Seek Medical CareObtain medical treatment as soon as possible.
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Severe cases of carbon dioxide toxicity progress to confusion, convulsions, and loss of consciousness.
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Talk with your health care provider about medications to treat motions sickness for an upcoming trip or cruise (seasickness).
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This finding may be the result of alteration in the colonic bacteria responsible for the reduction of sulfasalazine to sulfapyridine and mesalamine.
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February 22, 2010, 10:18:21 AM
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« Reply #19 on: February 22, 2010, 10:18:21 AM »

Digoxin (Lanoxin) increases the strength of the heart muscle to deal with the greater blood volume.
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The mean total dose administered in the pediatric clinical trial of flumazenil was 0.65 mg (range: 0.08 mg to 1 mg).
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During the period of myelosuppression, patients are at risk of developing infection and bleeding which may be life-threatening or fatal.
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Diagnosis is most often made by rinsing the nasopharynx and analyzing it to detect the presence of the influenza virus.
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In a third of the children with the disease, SD will recur, typically 1 ½ to 2 ½ years after the initial attack.
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However, the elevations are not expected to influence the effectiveness or safety of almotriptan.
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There may be an increased risk of low blood pressure and fainting when taking UROXATRAL in combination with blood pressure medication or nitrates, or erectile dysfunction medication.
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The fraction of a pseudoephedrine dose excreted in milk is estimated to be 0.4% to 0.7%. A decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.
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Irritation may also occur from poor hygiene on the part of the lens wearer.
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« Reply #20 on: February 22, 2010, 02:54:44 PM »

This can be seen in heart failure, kidney failure, and liver diseases like cirrhosis.
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This is a principal metabolite and inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase.
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Determination of serial plasma cortisol levels at 8 AM and for the 24-hour period following each treatment were used to calculate the plasma cortisol area under the curve (AUC0–24). In addition, 24-hour urinary-free cortisol levels were collected prior to initial treatment administration and during the period immediately following each dose.
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These reactions have usually responded promptly to the cessation of the infusion and administration of pressor agents, corticosteroids, antihistamines, or volume expanders as appropriate; however, the reactions can be fatal.
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Atenolol tablet, USP, should be used with caution in diabetic patients if a beta-blocking agent is required.
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Dosages of morphine should be chosen and must be titrated on the basis of clinical evaluation of the patient and the balance between therapeutic and adverse effects.
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During the study, no detectable activity was exhaled or excreted in the feces.
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Abrupt discontinuation of intrathecal baclofen, regardless of the cause, has resulted in sequelae that include high fever, altered mental status, exaggerated rebound spasticity, and muscle rigidity, that in rare cases has advanced to rhabdomyolysis, multiple organ-system failure and death.
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« Reply #21 on: February 22, 2010, 07:05:45 PM »

EXTRANEAL is used for the long dwell exchange (8- to 16- hours) in peritoneal dialysis.
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Regular follow-up care ensures that changes in health are discussed and that problems are treated as soon as possible.
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Tramadol hydrochloride and acetaminophen should not be used concomitantly with alcohol consumption.
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The viral particles are able to penetrate the skin and mucosal surfaces through microscopic abrasions in the genital area, which occur during sexual activity.
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A large, randomized, double-blind, controlled clinical trial was conducted in the US to compare the efficacy of AVELOX Tablets (400 mg once daily) to that of high-dose clarithromycin (500 mg twice daily) in the treatment of patients with clinically and radiologically documented community acquired pneumonia.
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Morphological and biochemical studies of endometrial suggest that 10–13 days of a progestin are needed to provide maximal maturation of the endometrium and to eliminate any hyperplastic changes.
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Absence of fever is also generally a good sign.
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Marine toxins are naturally occurring chemicals that can contaminate certain seafood.
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For high altitude pulmonary edema, the first treatment goal is to descend and bring the affected person to lower altitude if possible.
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Conversely, administration with inhibitors may reduce metabolism and potentiate methadone's effects.
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The patient may receive medications to controlfever or treat infection.
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« Reply #22 on: February 22, 2010, 11:27:31 PM »

Most states also test for other genetic disorders.
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Crohn’s disease may also cause sores, or ulcers, that tunnel through the affected area into surrounding tissues, such as the bladder, vagina, or skin.
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It can progress to diabetic ketoacidosis (DKA) or very high glucose levels (hyperosmolar coma) and result in unconsciousness and death.
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The patient should be informed of the potential risks and advantages of GLYNASE PresTab and of alternative modes of therapy.
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Many cities have local running clubs that sponsor races and offer training clinics for novices (also see the training plans below).
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If there is not enough time for the osteoblasts to produce more bone cells in the injured area; the micro fractures can join together to form a large enough area to cause a stress fracture.
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It has also been used to treat headaches, muscle and nerve pain, and stomach and bowel conditions such as Irritable Bowel Syndrome (IBS).
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IN THIS ARTICLEBirth Control Behavioral Methods IntroductionContinuous AbstinenceCoitus InterruptusNatural Family PlanningFertility Awareness MethodOther Methods of Periodic AbstinenceBreastfeedingDouchingFor More InformationWeb LinksSynonyms and KeywordsAuthors and EditorsDouchingDouching is a method of rinsing out the vagina.
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Major withdrawal symptoms (convulsions and delirium) may occur within 16 hours and last up to 5 days after abrupt cessation of these drugs.
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When amiloride is used concomitantly with a thiazide diuretic in patients without these complications, the risk of hyperkalemia is reduced to about 1-2%. It is thus essential to monitor serum potassium levels carefully in any patient receiving amiloride, particularly when it is first introduced, at the time of diuretic dosage adjustments, and during any illness that could affect renal function.
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In the United States, the exact prevalence rate of lens-particle glaucoma has not been reported.
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« Reply #23 on: March 01, 2010, 01:45:54 AM »

The lower clearance in women and the elderly results in higher concentrations of gemcitabine for any given dose.
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After proper administration of MUCOMYST (acetylcysteine), an increased volume of liquified bronchial secretions may occur.
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The leading role in osteoarthritis research is played by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), a part of the Department of Health and Human Services' National Institutes of Health (NIH).
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An injury to the spinal cord can damage a few, many, or almost all of these axons.
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However, because many drugs are excreted in human milk, caution should be exercised when ipratropium bromide nasal solution 0.03% (Nasal Spray) is administered to a nursing woman.
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One of the most common risks is for the needle to go too deep and cause a hole in the dura, the tissue that surrounds the spinal cord and nerve roots.
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These effects are usually transient and rarely require discontinuation of therapy.
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The USDA's Food Safety and Inspection Service (FSIS) has oversight over dairy, poultry, fruit, and meat products, except for shell eggs over which the FDA and USDA share jurisdiction.
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In the case of tremors secondary to exposure to toxins, the individual should be removed from the source of the toxins.
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« Reply #24 on: March 01, 2010, 06:59:58 AM »

This indicates that FINACEA Gel, 15%, does not increase plasma azelaic acid concentration beyond the range derived from nutrition and endogenous metabolism.
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The excretion of unmetabolized barbiturate is one feature that distinguishes the long-acting category from those belonging to other categories which are almost entirely metabolized.
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Up to 25% of people in the United States were vaccinated.
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Anuria, oliguria, or significant impairment of renal function (creatinine clearance under 60 mL per minute or clinically significant elevated serum creatinine) are contraindications (see [#section-6 CONTRAINDICATIONS]). Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to monitor renal function.
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Other studies have found that altered AMP-activated protein kinase activity is related to changes in the regulation of certain ion channels in the heart.
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There are sustained-release preparations that prolong the effects of the medication for several hours.
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Managing your emotions and the extra stress brought on by multiple sclerosis may mean making a few adjustments in your life, but stress can be managed.
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In most patients with RMSF, physicians will order other tests to determine how the patient is responding to the infection.
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« Reply #25 on: March 01, 2010, 12:17:10 PM »

This is similar, in some respects, to the retinal disorder that affects some premature newborns, although babies with IP are not usually born prematurely.
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Because of potential toxic effects on the fetus (See ADVERSE REACTIONS - “Gray Syndrome”), chloramphenicol should be given to a pregnant woman only if the potential benefit justifies the potential risk to the fetus.
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Among pill users who do not smoke, the risk of death was always lower than that associated with pregnancy for any age group, although over the age of 40, the risk increases to 32 deaths per 100,000 women, compared to 28 associated with pregnancy at that age.
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Actinic keratoses are thick, scaly lesions that form on the skin.
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IN THIS ARTICLEMeniere Disease OverviewMeniere Disease CausesMeniere Disease SymptomsWhen to Seek Medical CareExams and TestsMeniere Disease TreatmentSelf-Care at HomeMedical TreatmentSurgeryNext StepsPreventionOutlookSupport Groups and CounselingSynonyms and KeywordsAuthors and EditorsViewer Comments: Meniere Disease - Symptoms Experienced and Effective TreatmentsSurgeryMost people respond to medical management, but a few may need surgical treatment by a specialist to correct potential problems in the inner ear.
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Antioxidants: High doses of vitamin E (1000 units twice daily) may be beneficial in delaying functional deterioration in vascular dementia.
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Previous PageGlossaryNext Page »Next: Whooping Cough Symptoms »Viewer Comments & ReviewsWhooping Cough (Pertussis) - Describe Your ExperienceThe eMedicineHealth physician editors ask:Please describe your experience with whooping cough (pertussis).
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CARBOplatin may harm your developing fetus or breast-feeding baby.
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« Reply #26 on: March 01, 2010, 05:30:34 PM »

Victims may have a fever or a long-term infection or just a local inflammation.
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Oral contraceptives may cause edema (fluid retention) with swelling of the fingers or ankles and may raise your blood pressure.
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Certainly, more research is needed to unlock the mysteries of addiction, but this information adds one more link in explaining how the brain adapts in the addiction process.
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« Reply #27 on: March 01, 2010, 10:42:45 PM »

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Bronchoscopy involves inserting a flexible fiberoptic scope into the airway (trachea).
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Campylobacteriosis is diagnosed using laboratory test.
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Bleeding OverviewExtensive bleeding can occur either underwater or in the wilderness.
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Nitroglycerin is primarily used to treat and prevent angina associated with reduced blood flow to the heart.
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Rare: Bradyphrenia, Euphoric mood, Hallucination, Psychotic disorder, Suicidal ideation.
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A dose-related increase in wavy ribs was noted in the developing rat fetus when pregnant females received daily doses of approximately 212 times the maximum recommended human oral dose.
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Using an evidence-based approach, smoking was found to be more likely than not a risk factor for ALS based on two excellent studies by Kamel et al.
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Protein binding is saturable and at concentrations >20 μg/mL binding is non-linear.
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There are no well-controlled studies in women, but marketing experience does not include any evidence of adverse effects on the fetus following routine (short-term) clinical use of morphine sulfate products.
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Solutions should ideally be prepared in the hospital pharmacy under a laminar flow hood using careful aseptic technique to avoid inadvertent touch contamination.
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« Reply #28 on: March 02, 2010, 03:55:47 AM »

The pharmacokinetic profile of naltrexone suggests that naltrexone and its metabolites may undergo enterohepatic recycling.
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Adult GM1 is usually less severe and progresses more slowly than other forms of the disorder.
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Hydrochlorothiazide crosses the placental but not the blood-brain barrier.
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These data are from the International Federation for Gynecology and Obstetrics (FIGO), which publishes a report of treatment results submitted from around the world for a variety of cancers affecting women.
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Most people return to normal activities within a few days of having ICD surgery.
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They are made in the bone marrow and undergo a complex series of steps to gain functional maturity at which time they are released into the blood stream to perform their function.
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Obesity has long been known to be a risk factor for osteoarthritis of the knee.
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When the right ventricle fills with blood, it contracts (ventricular systole).
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Polymyositis and dermatomyositis are first treated with high doses of prednisone or another corticosteroid drug.
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Talk to your doctor if you are taking fluvoxamine and are pregnant or are planning to have a baby.
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Vorinostat reaches a peak concentration in the blood approximately four hours after a 400 mg dose.
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« Reply #29 on: March 02, 2010, 09:17:46 AM »

A person's immune system learns to recognize these surface proteins either by being infected with the flu virus and recovering or by getting a vaccine (flu shot) that contains similar H and N proteins.
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The typical failure rate of large numbers of pill users is less than 3% per year when women who miss pills are included.
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During the patch-free week, she may select an earlier Patch Day Change by applying a new ORTHO EVRA® patch on the desired day.
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In those patients who had levodopa dosage reduced, the dose was reduced on average by about 7%, 9%, and 13% in the placebo, 0.5 mg/day, and 1 mg/day groups, respectively.
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Warning signs or symptoms of fluid and electrolyte imbalance, irrespective of cause, include dryness of the mouth, thirst, weakness, lethargy, drowsiness, restlessness, muscle pains or cramps, muscular fatigue, hypotension, oliguria, tachycardia, and gastrointestinal disturbances such as nausea and vomiting.
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PRECOSE® may affect digoxin bioavailability and may require dose adjustment of digoxin by 16% (90% confidence interval: 8-23%), decrease mean Cmax of digoxin by 26% (90% confidence interval: 16-34%) and decreases mean trough concentrations of digoxin by 9% (90% confidence limit: 19% decrease to 2% increase).
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Allergy to latex (a natural rubber used in medical gloves, some types of elastic, balloons, and many other common items) is very common in people with spina bifida.
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Each panel member completed a conflict-of-interest statement and was asked to abstain from discussion of or voting on any recommendations they deemed to be a potential conflict of interest.
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Overall, about 1% of individuals with OHT develop glaucoma per year.
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